Supplementation with vitamin D can reduce pain in fibromyalgia and become a cost-effective alternative to other methods of therapy or adding to them. This conclusion was made on the basis of Austrian scientists conducted their study, whose results were published in the journal Pain.
Fibromyalgia - a chronic disease, the main feature of which are symmetrical musculoskeletal pain of varying intensity and localization, and the pain is not accompanied by tissue inflammation. The pain is usually associated with poor sleep, irritable bowel syndrome and chronic fatigue, a feeling of morning stiffness, a sense of swelling of extremities, fatigue, depression. Symptoms are aggravated by weather changes, fatigue, stress. The disease occurs in women twice as often than men. The causes of fibromyalgia are still unknown, what is connected with the absence of effective therapy of the disease. Methods commonly used to suppress the symptoms - physical therapy, psychotherapy, analgesics, as well as courses of antidepressants (duloxetine, amitriptyline), or antiepileptic drug pregabalin.
In addition, for patients with fibromyalgia is characterized by low levels of vitamin D (kaltsifediola) in the blood. The role of this substance in the symptoms of fibromyalgia has not yet been subjected to scientific study that led specialists from Medical University of Vienna and orthopedic hospital to hold the first of its kind, randomized, placebo-controlled study to evaluate the effect of raising kaltsifediola in the blood to reduce pain and general improvement of the patients.
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The study involved 30 patients with fibromyalgia, kaltsifediola level in the blood of less than 32 nanograms per milliliter. All participants were randomly divided into two groups, the first of which received oral supplementation with cholecalciferol (vitamin D3), and the second - a placebo. The goal of scientists conducted the study consisted in bringing in 20 weeks the level of serum kaltsifediola member of the first group to levels of 32 to 48 nanograms per milliliter. Indicators monitored by the fifth and 13th week of admission, and 25 weeks after the start of the course, and 24 weeks after its completion. Symptoms and general participants were determined by existing assessment methods, in particular the questionnaire Fibromalgia Impact Questionnaire.
It was found that in the group taking supplements, compared with the placebo group, from the very beginning of the course there was an overall improvement in disability, as well as a sharp decline in fatigue in the morning. However, intake of vitamin D had no significant effect on symptoms such as anxiety and depression. But the main result of the optimization level kaltsifediola serum was significant relief of pain in the group taking vitamin supplements, and this effect was maintained after 24 weeks after completion of the course.
"We are confident that the results are quite promising - said the lead author Vepner Florian (Florian Wepner). - Fibromyalgia accompanied by a wide set of symptoms, which, of course, can not only be explained by a deficiency of vitamin D. However, supplementation with this vitamin could be a safe and economical method of relief of patients with fibromyalgia who must regularly, especially in the winter, track vitamin Dv blood. Vitamin could be an alternative or complement to costly medical treatment and other therapies. "
At the same time, the authors emphasize that in order to confirm this hypothesis requires further clinical trials on a larger number of participants.